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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K3
All Species:
14.85
Human Site:
T302
Identified Species:
27.22
UniProt:
P46734
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46734
NP_002747.2
347
39318
T302
S
P
E
F
V
D
F
T
A
Q
C
L
R
K
N
Chimpanzee
Pan troglodytes
Q9XT09
393
43428
V338
S
L
E
F
Q
D
F
V
N
K
C
L
I
K
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546666
347
39324
T302
S
P
E
F
V
D
F
T
A
Q
C
L
R
K
N
Cat
Felis silvestris
Mouse
Mus musculus
O09110
347
39278
T302
S
P
E
F
V
D
F
T
S
Q
C
L
R
K
N
Rat
Rattus norvegicus
Q4KSH7
419
47517
F356
F
S
G
D
F
Q
S
F
V
K
D
C
L
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511595
352
40240
T307
S
P
E
F
V
D
F
T
A
Q
C
L
R
K
N
Chicken
Gallus gallus
Q90891
398
44059
V344
T
Q
D
F
Q
E
F
V
N
K
C
L
I
K
N
Frog
Xenopus laevis
Q07192
446
50082
T388
R
E
F
S
P
S
F
T
S
F
V
N
Q
C
L
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
V315
D
R
F
S
A
D
F
V
D
F
T
S
Q
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477162
334
38176
K290
F
I
A
V
C
L
Q
K
E
Y
M
A
R
P
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
F306
Y
S
L
P
L
V
K
F
I
N
T
C
L
T
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJV0
356
39818
V308
S
P
E
F
C
S
F
V
S
A
C
I
Q
K
D
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
V600
S
S
D
A
Q
D
F
V
S
L
C
L
Q
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.7
N.A.
99.1
N.A.
96.5
37.2
N.A.
89.7
30.3
42.1
75.3
N.A.
57
N.A.
37.7
N.A.
Protein Similarity:
100
47
N.A.
99.7
N.A.
98.8
56.7
N.A.
93.1
48.7
58
84.4
N.A.
72.9
N.A.
55.6
N.A.
P-Site Identity:
100
60
N.A.
100
N.A.
93.3
0
N.A.
100
40
13.3
13.3
N.A.
13.3
N.A.
0
N.A.
P-Site Similarity:
100
66.6
N.A.
100
N.A.
100
6.6
N.A.
100
66.6
26.6
20
N.A.
13.3
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.2
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
0
0
24
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
16
0
0
0
0
0
62
16
0
16
0
% C
% Asp:
8
0
16
8
0
54
0
0
8
0
8
0
0
0
8
% D
% Glu:
0
8
47
0
0
8
0
0
8
0
0
0
0
0
0
% E
% Phe:
16
0
16
54
8
0
77
16
0
16
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
8
16
0
8
% I
% Lys:
0
0
0
0
0
0
8
8
0
24
0
0
0
62
16
% K
% Leu:
0
8
8
0
8
8
0
0
0
8
0
54
16
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
16
8
0
8
0
0
54
% N
% Pro:
0
39
0
8
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
24
8
8
0
0
31
0
0
31
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
0
0
0
0
39
0
0
% R
% Ser:
54
24
0
16
0
16
8
0
31
0
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
39
0
0
16
0
0
16
0
% T
% Val:
0
0
0
8
31
8
0
39
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _